BLADDER PRESERVATION BY CHEMORADIOTHERAPY IN COMBINATION WITH RADICAL TUR-BT IN MUSCLE INVASIVE BLADDER CANCER

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[Bladder preservation by chemoradiotherapy in combination with radical TUR-Bt in muscle invasive bladder cancer].

PURPOSE To evaluate bladder preservation protocol by radical TUR-Bt and subsequent concurrent chemoradiotherapy in muscle invasive bladder cancer. PATIENTS AND METHODS Twenty-six patients with muscle invasive bladder cancer (T2-T4NOM0) were treated with concurrent chemoradiotherapy after transurethral resection of the tumor as much as possible beyond muscle layers. Chemotherapy was consisted ...

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Bladder Preservation for Muscle Invasive Bladder Cancer

The standard treatment for muscle invasive bladder cancer (MIBC) has been considered to be radical cystectomy (RC) with pelvic lymphadenectomy. However morbidity and impact on quality of life is significant. Radiotherapy has been used in MIBC patients who choose bladder preservation or who are unfit for RC with comparable outcomes. Evidence from some prospective and large retrospective series s...

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Organ preservation in muscle-invasive bladder cancer.

While organ preservation with nonextirpative surgery, radiotherapy, and frequently, chemotherapy has become a favored strategy in the treatment of many cancers, bladder preservation for patients with invasive disease remains controversial. The standard treatment for muscle-invasive bladder cancer in the United States is still radical cystectomy with pelvic lymph node dissection. An alternative ...

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Trimodality bladder preservation therapy for muscle-invasive bladder cancer.

Potentially curative treatments for patients with muscle-invasive bladder cancer (MIBC) are underused, especially in the elderly. Trimodality bladder preservation therapy, which includes a maximally safe transurethral resection of the bladder tumor, followed by concurrent chemoradiation, fulfills this currently unmet need. In multiple prospective clinical trials and large institutional series, ...

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ژورنال

عنوان ژورنال: The Japanese Journal of Urology

سال: 2007

ISSN: 0021-5287,1884-7110

DOI: 10.5980/jpnjurol1989.98.752